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6 Catechol-O-methyltransferase (COMT) - COMT has an influence on dopamine signaling in the prefrontal cortex, While the association of satisfied/Val with superior gait efficiency appears to become due to the impression of COMT on tonic dopamine regulation during the striatum in men only. The associations in between COMT, gait and executive operate have been influenced by gender. The COMT genotype was related to gait velocity in Gentlemen although not in Women of all ages.eight A further analyze showed that PA ranges, through dopamine regulation, moderates cognitive and mobility 瀏覽更多 gains by enhancing participation in PA. This system is probably because of genotypes which might be related to higher dopamine operate are connected with greater will increase in PA than genotypes connected with decreased dopamine perform.nine
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